Category: <span>Clinical Trials/Research/Emerging Treatments</span>

Category: Clinical Trials/Research/Emerging Treatments

Clinical Trials/Research/Emerging Treatments, Immunotherapy, Mesothelioma News, Pleural, Treatment

Study Shows Opdivo, Yervoy Effective After Mesothelioma Surgery

 

Patients with recurrent mesothelioma cancer often have few options. A new study by the Hyogo College of Medicine in Japan may have a potential answer.  This study tested the safety and efficacy of two drugs following mesothelioma surgery after cancer recurrence. The combination of immunotherapy drugs nivolumab and ipilimumab, known by the brand names Opdivo […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News, Treatment

Baylor Study: Mesothelioma ‘Staged Surgical Approach’ Increases Survival

 

Select patients diagnosed with mesothelioma cancer in both the thoracic and abdominal cavities still can achieve an extended survival if their treatment center performs the preferred types of aggressive surgery, according to a recent study at Baylor College of Medicine in Houston. Patients undergoing bicavitary cytoreductive surgery that includes the lung-sparing, extended pleurectomy and decortication […]

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Clinical Trials/Research/Emerging Treatments, Immunotherapy, Mesothelioma News, Pleural

Mesothelioma Surgery With Immunotherapy Proves Effective in Study

 

An immunotherapy combination given before aggressive surgery has shown impressive effectiveness in extending survival for pleural mesothelioma patients in a recent phase II clinical trial at Baylor College of Medicine. The combination of immune checkpoint inhibitors durvalumab and tremelimumab showed an ability to effectively alter the intratumoral immune system and make surgery more effective. This […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News, Treatment

Looking Beyond Clinical Trials for Mesothelioma Treatment

 

Clinical trial results should not always be the guiding force when a mesothelioma cancer patient and their medical team determine what therapy path to take, according to one recent study. A look at real-world populations might be just as important. A research team at the University of Pennsylvania Department of Medicine has made the point […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News

Global Mesothelioma Cases Nearly Double Over 30 Years

 

The number of people in the world diagnosed annually with mesothelioma cancer has almost doubled in the last 30 years, accentuating the need for more effective and better coordinated efforts to end this preventable, global health problem. Almost 35,000 people were diagnosed with mesothelioma in 2019, compared to an estimated 19,000 in 1990, according to […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News, Surgical procedures

Latest Study Compares Major Pleural Mesothelioma Surgeries

 

Mesothelioma patients may benefit more from aggressive extrapleural pneumonectomy surgery than from the lung-sparing pleurectomy and decortication currently being recommended as an alternative by many specialists today. According to the most recent study from Italy, extrapleural pneumonectomy, or EPP, allowed mesothelioma patients diagnosed with high symptom burden to live a longer, better-quality life than with […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News, Pleural

New Research Focuses on Mesothelioma Brain Metastasis

 

Distant metastasis is common with malignant pleural mesothelioma – more than 60% of patients experience it – but rarely is it found around the brain. A new study by a team of radiation oncologists in Great Britain, however, suggests that physicians should increase their focus on potential cerebral metastasis in mesothelioma patients. “Patients will continue […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News, Treatment

Study: ‘Drug-Factory’ Technology Kills Mesothelioma Tumor Cells in Mice

 

Tiny, drug-producing beads implanted in the chest cavity could one day provide a powerful platform that would change the way mesothelioma cancer is treated. In a recent study, researchers from Rice University and the Baylor College of Medicine demonstrated the implants’ impressive effectiveness in mice, raising hopes of a possible breakthrough for this tough-to-treat cancer. […]

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Clinical Trials/Research/Emerging Treatments, diagnosis, Mesothelioma News, Pleural

Blood Serum Diagnostic Test for Mesothelioma Explored in Study

 

One of the biggest obstacles to treating pleural mesothelioma cancer effectively is its often late-stage diagnosis. A recent study shows encouraging signs that those days could be ending. Novel diagnostic testing using blood serum and infrared spectroscopy is being explored to better characterize and differentiate mesothelioma in its early stages from other lung diseases and […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News, Pleural

Mesothelioma Clinical Trial Studies Keytruda, Lenvatinib Combination

 

A possible second-line treatment for pleural mesothelioma may be on the horizon after a phase II clinical trial showed impressive efficacy with early returns from the Netherlands Cancer Institute in Amsterdam. The single-arm, open-label clinical trial involved the combination of pembrolizumab, an immunotherapy drug known by the brand name Keytruda, in combination with lenvatinib. Synergy […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News, Peritoneal

Study Suggests Relationship Between Stromal Tumors and Mesothelioma

 

Early identification of peritoneal mesothelioma cancer – when it is most effectively treated – may become more common after a recent study revealed a potential link to gastrointestinal stromal tumors. A single-center retrospective review by the division of surgical oncology at University of California San Diego Moores Cancer Center identified a previously underrecognized, synchronous co-occurrence […]

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asbestos exposure, Clinical Trials/Research/Emerging Treatments, Mesothelioma News

Study: Those Exposed to Asbestos Should Not Take Beta-Carotene

 

Taking beta-carotene health supplements could increase the risk of lung cancer or death from cardiovascular disease for anyone who is regularly exposed to asbestos, according to a panel of medicine experts. Based on existing scientific evidence, the U.S. Preventive Services Task Force concluded recently that the potential harms of beta-carotene supplements outweigh any benefits, particularly […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News, Pleural

Researchers in Japan Study Inhalable Gene Therapy for Mesothelioma

 

Patients with malignant pleural mesothelioma may be turning to orally inhalable gene therapy in the future, easing the treatment burden for this cancer with no cure. The recent focus on identifying genetic mutations that make individuals more susceptible to certain cancers – including mesothelioma – has led to related research on how best to combat […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News

Drug Repurposing Study Could Identify New Mesothelioma Treatments

 

The next breakthrough in the treatment of malignant mesothelioma may be quietly underway. An international research team based at Temple University in Philadelphia recently identified four drug compounds – already being used safely for noncancerous conditions – that have shown impressive potential for treating mesothelioma. They were part of a novel drug repurposing project aimed […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News

Toronto Cancer Center Hosts SMARTEST Mesothelioma Clinical Trial

 

Princess Margaret Cancer Centre in Toronto recently opened a first-of-its-kind clinical trial that hopes to build on earlier pioneering efforts to turn pleural mesothelioma into a more manageable, potentially survivable disease. Expectations are high. This single-center phase II clinical trial is named SMARTEST, and follows in the wake of earlier mesothelioma trials SMART and SMARTER […]

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