Category: <span>Clinical Trials/Research/Emerging Treatments</span>

Category: Clinical Trials/Research/Emerging Treatments

asbestos exposure, Clinical Trials/Research/Emerging Treatments, Doctors/Specialists, mesothelioma, Mesothelioma News

Early Detection Tests for Mesothelioma Are in Development

 

Scientists in Australia are developing early detection tests for mesothelioma. The Asbestos and Dust Diseases Research Institute’s new test could potentially save lives. According to ADDRI’s academic and research director Dr. Anthony Linton, the tests will be similar to PCR tests already in use to detect COVID-19. These new tests can find small amounts of […]

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Clinical Trials/Research/Emerging Treatments, Immunotherapy, mesothelioma, Mesothelioma News

Phase I Trial Improves Mesothelioma Survival More Than 200%

 

Sellas Life Sciences reports its Phase I clinical trial showed improvement of overall survival in patients with pleural mesothelioma. The study focused on a new potential therapy called GPS (galinpepimut-S), an immunotherapy vaccine. The trial included 10 patients with relapsed or refractory mesothelioma, nine of whom received at least three doses of GPS. Researchers gave […]

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Clinical Trials/Research/Emerging Treatments, Immunotherapy, mesothelioma, Mesothelioma News

Early Mesothelioma Vaccine Testing Shows Promise

 

Sellas Life Sciences reports its Phase I clinical trial showed improvement of overall survival in patients with pleural mesothelioma. The study focused on a new potential therapy called GPS (galinpepimut-S), an immunotherapy vaccine. The trial included 10 patients with relapsed or refractory mesothelioma, nine of whom received at least three doses of GPS. Researchers gave […]

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Asbestos (general), asbestos exposure, Clinical Trials/Research/Emerging Treatments, Mesothelioma News

CARD Clinic to Release New Asbestos Research in 2024

 

The Center for Asbestos Related Disease has begun work on a series of new research articles scheduled to be released throughout 2024. The content will center around new studies concerning asbestos and autoimmune disease.  The articles will reveal details discovered in analyzing the health impact of people exposed to amphibole asbestos from Libby, Montana. This […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News, Treatment

Polaris Submits Application for New Mesothelioma Treatment

 

Multinational biopharmaceutical company Polaris Group announced their application for a rolling submission of a new mesothelioma treatment this month. The Biologic License Application for the experimental drug ADI-PEG 20 is the first step in U.S. Food and Drug Administration approval.  The application outlines the use of ADI-PEG 20 for non-epithelioid mesothelioma alongside treatment with pemetrexed […]

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asbestos exposure, Clinical Trials/Research/Emerging Treatments, Legal, Mesothelioma News

Talc Researcher Asks Court to Dismiss J&J Lawsuit Against Her

 

A medical researcher responsible for uncovering a potential link between talc and cancer has petitioned a judge to dismiss the lawsuit pharmaceutical giant Johnson & Johnson filed against her.  Dr. Jacqueline Moline maintains that her 2019 study linking cosmetic talc products and cancer is sound and protected by the First Amendment. Moline has served as […]

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asbestos exposure, Clinical Trials/Research/Emerging Treatments, Mesothelioma News

Study Finds Link Between Asbestos Exposure and Autoimmune Conditions

 

Asbestos is widely known as an occupational hazard, but emerging evidence suggests that prolonged exposure to environmental asbestos could lead to severe autoimmune conditions, according to a study by Montana State University researchers. Microbiology and immunology research associate Dr. Jean Pfau and a team of researchers discovered the connection to a specific type of asbestos […]

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Clinical Trials/Research/Emerging Treatments, Mesothelioma News, Treatment

Mesothelioma Immunotherapy Receives Orphan Drug Designation

 

A novel therapy for mesothelioma has been given orphan drug designation by the U.S. Food and Drug Administration.  Avenge Bio, a biotechnology company working on a new treatment platform for immunotherapy, announced it was granted the designation for its drug  AVB-001 in June. It is currently enrolling patients in ongoing phase 1 and phase 2 […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News

Phase 3 Keytruda, Chemotherapy Mesothelioma Trial Shows Promising Results

 

Pharmaceutical company Merck says use of its immunotherapy drug Keytruda in conjunction with chemotherapy increases the survival rate for people with advanced pleural mesothelioma, according to the latest results of a phase 3 clinical trial. The results were announced in June at the annual meeting of the American Society of Clinical Oncology. They showed Merck’s […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News

New UMD Study Shows How Mesothelioma Can Spread

 

Researchers at the University of Maryland are getting a better idea of why mesothelioma takes decades to develop in the body. In a 2023 paper published in the journal Environmental Research, a team of researchers at the University of Maryland found that understanding mesothelioma involves the way immune cells “sense” and interact with particles around […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News

Patients Needed for New Mesothelioma Clinical Trial

 

A new investigational drug for mesothelioma can now begin human trials after it was granted fast-track designation by the U.S. Food and Drug Administration last week. The novel treatment, SnyKIR-110, is a T-cell therapy designed to treat patients with mesothelioma, cholangiocarcinoma (bile duct cancer) and ovarian cancer.  “We are thrilled to receive fast-track designation from […]

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asbestos exposure, Clinical Trials/Research/Emerging Treatments, Mesothelioma News

Global Mesothelioma Incidence Report Assesses Risk Factors

 

A new study published in the Journal of Thoracic Oncology has evaluated the global burden of mesothelioma. The report analyzes trends by age, sex and geographic location to assess risk factors on a population level.  Northern Europe, Australia and New Zealand reported the highest incidence rates, according to the study. The age-standardized rate of mesothelioma was […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News

New BAP1 Finding Could Be Key to Regulating Mesothelioma

 

Mesothelioma is a rare cancer most often caused by exposure to asbestos fibers. Our researchers at the University of Hawaii Cancer Center have discovered how asbestos causes mesothelioma, which we linked mainly to the protein HMGB1.  After several years of studying a unique mesothelioma epidemic in Cappadocia, Turkey, we noted that in certain families, up […]

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Clinical Trials/Research/Emerging Treatments, mesothelioma, Mesothelioma News, Treatment

Netherlands Cancer Institute Tests New Mesothelioma Therapy

 

Research for a new type of mesothelioma treatment is underway at the Netherlands Cancer Institute. Scientists are exploring a novel combination of existing medications for patients with BAP1 genetic mutations.  More than half of all mesothelioma patients show alterations in the BAP1 tumor-suppressor gene. An altered BAP1 gene allows for vulnerabilities that make specific treatments […]

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Clinical Trials/Research/Emerging Treatments, Immunotherapy, mesothelioma, Mesothelioma News, Treatment

Mesothelioma Treatment Uses Natural Immune Cells

 

For patients with mesothelioma cancer, immunotherapy is a promising new field. Results from a recent study at Rice University in Houston are exciting. Researchers are looking at ways the natural immune system can help fight this cancer.   The study examined the therapeutic effects of interleukin 2, a form of immunotherapy for mesothelioma. IL2 is a […]

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