Author: <span>Walter Pacheco</span>
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New Zealand Asbestos Guide Aims to Reduce Deaths

 

New Zealand has a new guide for managing and removing asbestos in the workplace. The “Approved Code of Practice for the Management and Removal of Asbestos,” or ACOP, was designed to complement the Health and Safety at Work (Asbestos) Regulations 2016. Described as the first for the country, the new guide hopes to cut asbestos-related…

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Asbestos Mining Town in Canada Searches for New Identity

 

Asbestos wasn’t always an ugly word. Once hailed as a miracle fiber in manufacturing and construction, it is now scorned for its toxicity and link to mesothelioma and other deadly respiratory diseases. Perhaps no place knows that fall from grace better than the small town of Asbestos in southeast Quebec. Not only did the asbestos…

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Red Wine Chemical Enhances Mesothelioma Chemotherapy

 

A new experimental treatment combining a chemical found in red wine and a popular chemotherapy drug showed a powerful synergistic effect in targeting pleural mesothelioma cells. Researchers at Soon Chun Hyang University Hospital Cheonan in South Korea combined the platinum-based chemotherapy drug cisplatin with resveratrol, a natural antioxidant found in wine and red grapes. The…

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Using Keytruda for Mesothelioma May Become a Reality

 

The U.S. Food and Drug Administration recently upgraded its approval of pembrolizumab (Keytruda) for metastatic non-small cell lung cancer, inching it closer to becoming an accepted treatment option for pleural mesothelioma. Pembrolizumab, produced by pharmaceutical giant Merck & Co., also is marketed as Keytruda. The FDA’s announcement last week converted its previous “accelerated” approval in…

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Definitive Radiation Therapy Extends Mesothelioma Survival

 

Patients with pleural mesothelioma are missing a chance to increase survival time because they are underutilizing definitive radiation, according to a recent study by the Icahn School of Medicine at Mount Sinai in New York City. A team of doctors found that overall survival at the two- and five-year marks almost doubled for the small…

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Hoboken Train Crash Stirs Asbestos Concerns

 

High asbestos levels and extensive debris delayed the federal investigation of the Hoboken train crash in New Jersey for more than a week, officials said. Although officials reopened the majority of the rails at the Hoboken terminal this week, efforts to completely clean the century-old terminal will take even longer. The Sept. 29 crash killed…

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Researchers Treat Mesothelioma with Precision Medicine

 

Targeted therapy aimed at specific genetic mutations can lead to significant improvement in progression-free survival for many cancer patients, including those with mesothelioma, a recent study shows. The research team at Intermountain Precision Genomics in St. George, Utah, found that matching tumor-related genetic mutations to drugs specific to the corresponding abnormality slows or stops many…

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Peritoneal Mesothelioma Grading System Improves Prognosis

 

The first two-tier grading system for peritoneal mesothelioma has produced a significant subset of patients with an incredible median overall survival of nearly 12 years. That pathology-based grading system should provide patients with a more accurate prognosis, potentially helping doctors design more personalized and effective therapies. “We can tell patients now what the future holds….

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Sugarbaker: Mesothelioma Clinical Trial May Be ‘Home Run’

 

Thoracic surgeon and mesothelioma visionary Dr. David Sugarbaker already is thinking two steps ahead, anticipating the optimal utilization of this latest clinical trial drug combination. That’s what leaders do. A phase II, multicenter clinical trial involving the antibody-drug conjugate anetumab ravtansine (BAY 94-9343) for patients with stage IV pleural mesothelioma opened recently with considerable expectations,…

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Sugarbaker: Mesothelioma Clinical Trial May Be ‘Home Run’

 

Thoracic surgeon and mesothelioma visionary Dr. David Sugarbaker already is thinking two steps ahead, anticipating the optimal utilization of this latest clinical trial drug combination. That’s what leaders do. A phase II, multicenter clinical trial involving the antibody-drug conjugate anetumab ravtansine (BAY 94-9343) for patients with stage IV pleural mesothelioma opened recently with considerable expectations,…

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FDA Speeds Possible Second-Line Treatment for Mesothelioma

 

The U.S. Food and Drug Administration awarded Fast Track designation recently to the WT1 cancer vaccine, moving it closer to becoming the first approved second-line treatment for malignant pleural mesothelioma. The vaccine, also known as galinpepimut-S, is an immunotherapy agent that targets the WT1 protein, which is expressed in high levels in various cancers, such…

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Study: Onconase, Malaria Drug Extends Mesothelioma Survival

 

A new treatment combining two existing drugs — one derived from frog eggs and another given to combat malaria — may be the key to extending mesothelioma survival. Scientists at Tongji University in Shanghai, China, discovered that mixing Onconase, an enzyme present in early-stage leopard frog embryos, with antimalarial drug dihydroartemisinin (DHA) synergistically suppressed growth…

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New Lung Cancer Study May Improve Mesothelioma Therapy

 

New insight into the gene responsible for the most aggressive subtype of non-small cell lung cancer (NSCLC) could bring hope for mesothelioma patients. Researchers from UT Southwestern Medical Center identified a new way to target lung cancer through the Kirsten rat sarcoma viral oncogene homolog, also known as the KRAS gene. Tumors that carry a…

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Orlando Won’t Face Fines for Exposing Firefighters to Asbestos

 

City of Orlando and Orlando Fire Department officials will not face any fines after firefighters were exposed to asbestos during a training exercise in February. Investigators met with Orange County Environmental Protection Division (EPD) officials and decided not to impose any penalties, which could have amounted to $25,000 for each violation. Instead, fire department officials…

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Sen. Boxer: EPA Should Include Asbestos in Top Priorities

 

Selecting the 10 most dangerous chemicals in the U.S. is the first order of business under the recently strengthened arm of the Environmental Protection Agency. “EPA must consider all forms of asbestos in this initial list of chemicals it acts on,” U.S. Sen. Barbara Boxer, D-Calif., wrote in an Aug. 26 letter to EPA administrator…

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