New York, Oct 12: Researchers have found how aspirin works in the body to target an inflammatory protein linked to a variety of diseases, such as rheumatoid arthritis, heart disease, and certain cancers. Aspirin is one of the oldest and most commonly used medicines, but many of its beneficial health effects have been hard for scientists and physicians to explain.The new study conducted by researchers at the Boyce Thompson Institute and Rutgers University in US and San Raffaele University and Research Institute in Italy, shows that salicylic acid, an active metabolite of aspirin, blocks HMGB1, which may explain many of the drug’s therapeutic properties.
