BackgroundEndometrial cancer that occurs concurrently with peritoneal malignant mesothelioma is difficult to diagnose preoperatively.Case presentationA postmenopausal woman had endometrial cancer extending to the cervix, vagina and pelvic lymph nodes, and PMM in bilateral ovaries, cul-de-sac, and multiple peritoneal sites. Adjuvant therapies included chemotherapy and radiotherapy.